1) Definition and importance of erectile dysfunction:
"Erectile dysfunction (ED), sometimes referred to as" male / powerlessness "(or" impotence "only), is the inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse (coitus) / sex. Erectile Dysfunction is different from other conditions than normal sexual relations with affect, such as lack of sexual desire (libido) and ejaculation / orgasm disorders. However, a number assignedSexual disorders occur in May and a significant suffering (morbidity) for patients.
DE, well connected, so that cultural conceptions of power, success and masculinity, a devastating psychological consequences including feelings of shame, loss or failure. ED is a serious violation of human relations and self-esteem. It affects millions of people around the world with implications that go far beyond sexual activity alone. In 45 years, many people have experienced at least one andLife. Many people are reluctant to erectile dysfunction with their women and their physicians and thus underestimate discuss the condition.
Although erectile dysfunction can occur at any age, usually the oldest, the greater the risk.
– The basic idea: ED is a common and dangerous disease important in people's lives.
2) anatomy and physiology of erection:
The penis contains two chambers, as a result, the spongy tissue, which extends along the top of the penis. TheUrethra, which is the channel for urine and ejaculate, runs the lower part of the corpus cavernosum. Filling the corpora cavernosa is a spongy tissue consisting of smooth muscles, connective tissues, spaces, veins and arteries. A membrane called the tunica "tunic", surrounds the corpora cavernosa. Veins located in the albuginea of blood from the penis.
The erection of the penis can be induced by two different mechanisms. The first is the assembly of reflection obtainedto touch gently, directly and continuously, and rubbing the body of the penis.
The second is the psychogenic erection, which is obtained by erotic fantasies, fantasy or dream.
Thus, sexual stimulation, the tactile (reflex), or mental / psychological, can go generates electrical impulses to the nerves around the penis and causes the nerves to release nitric oxide (NO), which in turn increases the production of cyclic GMP (cGMP) in smooth muscle of the corpora cavernosacavernosa. The cGMP causes the smooth muscle relaxation of the erectile tissue and allows a quick diagnosis, which flows into the penis (the blood fills the corpora cavernosa, the penis was bigger, stronger and thicker). The pressure compresses the veins of the albuginea, then, begin to contribute to the blood in the erectile tissue, that is, erect. The assembly is reversed when the levels of cGMP in the corpora cavernosa fall, allowing the smooth muscles of the corpora cavernosa toTermination of contracts in the blood and opening veins that the blood from the penis. The levels of cGMP in the corpora cavernosa fall because it is inactivated by an enzyme called phosphodiesterase type 5 (PDE5).
– Some basic ideas: the erection of the penis caused by sexual stimulation and arousal (physical or psychological), the swelling and enlargement of the penis due to local accumulation of blood, due to a pressure of expansion. Increased levels of nitric oxide(NO), is again increasing cyclic GMP (cGMP) – the most important vasodilator cascade of molecular promote erection.
3) Causes (Etiopathogenesis) and Pathophsiology ED:
There are many possible causes of erectile dysfunction, which are usually in 3 categories: Organic / Somatic; psychogenic / psychological needs, Mixed / Misc Each of these classes can have subclasses as an effective means to organize, prioritize, and each case.
Organic / Somatic arethe origin lies somewhere in the body in an organ or tissue, not in mind nor thoughts / emotions. So there are a number of diseases may cause erectile dysfunction – the endocrine system (such as hormones and glands associated with are, for example: hypogonadism, hyperprolactinemia), vascular (arteries and / or veins, such as: arteriosclerosis l ', hypertension, dyslipidemia, diabetes, metabolic syndrome), neurological (nervous system, the central nervous system (CNS) and / or peripheral nervous system (PNS), for example, the spine center), Spinal injury, neuropathies, Parkinson's, Alzheimer's disease, multiple sclerosis, stroke, drug-induced (many drugs can cause ED as a side effect – and some antidepressants, antihypertensive drugs are often associated with impaired dysfunction, but there are many more drugs have the potential for erectile dysfunction).
Generally Organic / Somatic are associated with a worse prognosis, atherosclerosis, today, an event known as "guardians" in cardiovascular disease, metabolic syndrome and diabetesmellitus.
Psychogenic / psychological causes of erectile dysfunction are more common than global, and young men could be affected – the sexually inexperienced young man, without disease may, during the first sexual activity with her partner has ED because it can become a "fear of failure or disappointing their partner. " The belief that the erection does not develop, if necessary, is therefore a self-fulfilling prophecy.
And secondly, for all ages, men who live in conditions of psychological stressCan) (overwork, lack of sleep, personality conflicts depressed, anxious, helpless and feel) the lack of libido (sexual desire. Then, in May and strengthen ED arise there are concerns, and thus a vicious circle can be determined, and very difficult to treat.
Increased sympathetic vasoconstrictor tone, with high blood circulating norepinephrine / epinephrine levels, seems to play an important role in mental health. The sympathetic branch of the autonomic nervous system is usuallyactivated in stress situations, preparing the body for 'fight or flight "response, version 2 main catecholamines (norepinephrine = noradrenalin is directly secreted by sympathetic nerves and adrenaline = epinephrine released by the adrenal glands above = adrenal glands, after stimulation the sympathetic nerves). This catecholamines induce vasoconstriction (narrowing of arteries) that occur assembly difficult.
Although uncommon, can be increased with ED associatedsevere psychiatric disorders such as depression, schizophrenia, drug abuse, panic disorder, generalized anxiety disorder, personality disorders.
There are many other possible causes of erectile dysfunction (mixed / other), but they are relatively rare – disorders of the penis associated with ED (other primary diseases of the penis, for example, Peyronie's disease, epispadias, Post-priapism), blood diseases (blood – the disease, for example): sickle cell anemia, leukemia, liverLiver cirrhosis, hemochromatosis, scleroderma …
All causes of erectile dysfunction will converge to a common effect – the enlargement of the arteries of the penis with blood and therefore local capture occurs.
The diagnosis of erectile dysfunction is usually initiated in relation to the patient, and later the study of nocturnal erections (NPT) is the diagnostic test and then asked to confirm the suspected diagnosis. NPT is the erection of the penis during sleep spontaneously. AND all persons without this phenomenon,usually several times during sleep. Thus, examination of the NPT is central to the ED to diagnose because it is a psychological cause (most common) or may indicate an organic cause – patients with psychogenic ED have nocturnal erections, which means that a biological basis for the somatic and their ED.
– The basic ideas: Although ED can be caused by many conditions or serious illnesses are often occurs in people who were in good health, and are temporarily in severe psychological distress,translated by a bad lifestyle, characterized by anxiety, poor sleep and poor nutrition, resulting in a general malaise and weakness DE.
The causes of erectile dysfunction in response to a sequence that overlap – there is enlargement of the arteries of the penis, so that there are no local storage of blood as possible.
The diagnosis of erectile dysfunction is confirmed by the NPT.
4) the natural alternatives for the treatment of erectile dysfunction is worth the effort!
Anyone with the name "known Viagra", "Levitra" and"Cialis".
Viagra (Sildenafil), Levitra (Vardenafil) and Cialis (tadalafil), drugs known as PDE5 inhibitors and are commonly prescribed for the treatment of erectile dysfunction. Few drugs have received much attention and recognition, such as Viagra / Levitra / Cialis, in part because of marketing efforts and costs, the pharmaceutical companies.
All agree, yes, Viagra / Levitra / Cialis do not work … But at what cost to your health? "As with all chemical drugs, there are risks and side effectsImpact of Viagra / Levitra / Cialis. These drugs have potential side effects and should be informed about all the people, taking into account the intake of these drugs. Viagra / Levitra / Cialis side effects are generally mild to moderate (but not very frequently, sometimes side effects can be serious or life threating). They usually last from minutes to hours after dosing. The most common side effects are: nasal) (nasal congestion, headache, flushing (faceIrregular heartbeat),), dyspepsia gastrointestinal (indigestion. most serious side effects are possible: either the vision of sudden hearing loss, angina (chest pain or heaviness), cardiac arrhythmia (irregular heartbeat), dyspnea (shortness short), edema (swelling), (priapism painful condition of the erect penis before it is too flaccid state despite the absence of stimuli for both physical and mental, for a period of at least four hours). On the other hand, there is possibilityOthers who may be psychologically dependent on him, able to get erections without taking Viagra / Levitra / Cialis. Not surprisingly, many people seek alternative, less hazardous natural products that work well and have no side effects. These Viagra / Levitra / Cialis alternatives are not chemical drugs, and offer a natural and delicate in terms of improved sexual health and general welfare. Unlike Viagra / Levitra / Cialis is a natural alternativewithout a prescription, so they are easily accessible – people should not receive time and money, only for the prescription sheet, and avoid the humiliation, and embarrassing interviews. Furthermore, natural Viagra / Levitra / Cialis alternatives are less expensive and more positive actions. Increase blood flow, not just the genitals, but to all body organs including the brain. They are also the bodies of several nutritional compounds such as amino acids, vitamins and mineralsimportant for a healthy life. Thus, the natural alternatives are worthwhile because they work well, are safe and inexpensive.
5) the best natural products for the treatment of erectile dysfunction:
Many natural products can help men with erectile dysfunction, especially when organized:
=> Food (nutrition) Extras:
– L-arginine (amino acids)
– Minerals: zinc, selenium, magnesium
– DHEA (De-Hydro-Epi-Androsterone)
=> Herbs / Plants / Vegetals and related natural products (Phytotherapy):
–Yohimbine;
– Panax (Asian) Ginseng;
– Tribulus terrestris;
– Ginkgo biloba;
– Muira Puama (Ptychopetalum scanner developed / olacoides Ptychopetalum);
– Maca (Lepidium meyenii);
– Damiana (Turnera diffusa / Damiana);
– Forskolin (Coleus Forskohlii);
– Pycnogenol
=> Other Natural Products:
– Deer Antler Velvet
L-Arginine is an amino acid.
L-arginine is the precursor for the synthesis of nitric oxide (NO)(The production of cGMP is subsequently increased), and is also needed for the synthesis of creatine, and so their oral intake of advantage not only in men with erectile dysfunction, it has many important health benefits in general:
#] Increases blood flow in the arteries of the body (not only), but also in the genitals;
#] Male fertility / infertility, improving sperm production and motility;
#] Lowers blood pressure (much) For people with hypertension;
#] Reduces body fat (excellent for overweight or) obese persons;
#] Improvement of insulin sensitivity (excellent) for diabetics;
#] Reduces the risk of serious heart disease) (eg, heart attack;
#] Increases muscle mass (athletes like it!)
#] Stimulates the secretion of hormones important in anti-aging body (GH = growth hormone);
#] Improves immune function;
#] Reduces the time of wound healing.
Zinc, asSelenium and magnesium, is an indispensable element (mineral) needed to sustain life. Many proteins in the human body zinc prosthetic groups, a genre, the "zinc finger-play. It 'a cofactor in many biological processes, including DNA, RNA and protein synthesis. Approximately 30% of zinc is in the cell nucleus. A large amount of proteins that play a role in the regulation of gene expression is due to zinc.
InMen have testicles and prostate particularly high concentrations of zinc. The sites where male hormones to bind to cells (androgen receptors) require zinc to function properly.
Zinc deficiency significantly reduces the rate of testosterone, sperm production and can reduce the life span of ejaculated sperm, as well. Male fertility seems to be influenced by zinc. Infertile men have less seminal fluid zinc, with normal or decreased blood zinc. Short-term zinc depletion leads to foodDecrease in serum testosterone, seminal volume and total seminal zinc loss per ejaculate. Zinc supplementation improves semen parameters in men with reduced sperm motility. The levels of zinc seem to fall into the prostate tissue and prostatic fluid in men with prostate cancer.
Zinc also plays a role in immune defense, wound healing, coagulation behavior and learning, taste and smell, blood, the role of thyroid hormones and insulin action. In addition, zincLiver, which may be incurred for the synthesis of "retinol-binding protein (RBP), the transport protein of vitamin A. Without enough zinc, symptoms of vitamin A, vitamin supplementation despite extensive.
Magnesium, zinc and selenium is a mineral that is extremely important as a cofactor of several enzymes in biochemical reactions in the body. It plays a key role in the production and transfer of biological energy (ATP = adenosineTri-phosphate) in muscle contraction and relaxation, nerve conduction, in protein synthesis …
How is closer to erectile dysfunction, it should be noted that magnesium promotes the synthesis of nitric oxide (NO), a rapid increase in the cGMP signal transduction, the dilation of the arteries – as already mentioned, the physiological basis the erection of the penis.
Beyond DE, magnesium is very important for other diseases and health whereMagnesium intake should always be encouraged. The same ideas are valid for selenium …
Selenium is an important component of the system of glutathione peroxidase, as an antioxidant. It works in conjunction with vitamins A, C, E to prevent oxidative damage in cells ( "oxidative stress"). Reactive oxygen species (ROS) are free radicals from oxygen metabolism. The production of ROS, like superoxide (O2-), hydrogen peroxide (H2O2) and hydroxyl radical (OH-), conventionallyoccurs in cells. ROS play an important role in many physiological processes in cells. "Oxidative stress is a condition that occurs when there are high levels of antioxidant defenses ROS victory against oxidative damage. This is the pathophysiological basis of diseases. All the organs of the body must be sufficiently strong antioxidant defense. Selenium is not only useful for the reproductive organs, all organs healthy with it!
Pycnogenol acts as aAntioxidant. This is an extract from the bark of French maritime pine. Pycnogenol contains several active ingredients, including flavonoid monomers such as catechin, epicatechin and Taxifolin. It contains condensed procyanidins call (also known as flavonoids and proanthocyanidins), as procyanidin B1, B3, B6 and B7, the dimers, oligomers and polymers of catechin and epicatechin are. Pycnogenol also contains phenolic acids including gallic acid, p ferulic acid, caffeic acid, vanillic acid, coumaric acid,Protocatechuic and p-hydroxy acids and their glycosides and esters of glucose.
Ginkgo biloba is a strange kind of tree without congeners Chinese who live nearby. The useful parts of ginkgo are the leaves and seeds. Ginkgo leaf extract of ginkgo is the most commonly used is usually in the form of too much. Ginkgo leaf and its extracts contain many active ingredients such as flavonoids, terpenes and organic acids. Many extracts from the leaves of Ginkgo is standardized to contain 24% to 25%Flavonoid glycosides and 6% terpenoids. Flavonoids derived primarily from main rutin Flavonol and include isorhamnetin, quercetin, kaempferol, and proanthocyanidins. Terpenes primaries are ginkgolides A, B, C, M and J and bilobalide. Although many of the voters of the ginkgo have intrinsic pharmacological effects individually, there is no evidence that the components work together to produce pharmacological effects stronger than any individual component. Ginkgo LeafProducts have an antioxidant effect, inhibits platelet aggregation (blockage of blood clotting, blood-thinning effect), and also relax the smooth muscles in the arterial wall and thus improves the blood circulation. These are the reasons for which the products of ginkgo leaves are so important for people with erectile dysfunction and / or many other conditions.
Forskolin is a labdane diterpene from the Indian plant Coleus (Coleus Forskohlii product). Forskolin stimulates and activates the enzyme adenylyl cyclase in heart andvascular smooth muscle. This drives the overproduction of cyclic AMP (cAMP), leading to increased calcium channels and the concentration of intracellular calcium, (leading to increased contractility of cardiac muscle and smooth muscle relaxation of the Open so that it acts as a vasodilator).
Panax ginseng is used as an adaptogen to increase resistance to environmental pressures and as a general tonic to improve wellness. The useful part of Panax ginseng is the root. It contains severalThe active ingredients. The main ingredients are triterpenoid saponins called ginsenosides panaxosides or collectively. Other components of pectin, B vitamins, flavonoids and different.
Panax ginseng has vasodilator and antioxidant actions, and also enhances the libido.
Maca (Lepidium meyenii) is a very resistant plant has long been cultivated in the Andes. The relevant part of Maca is the root. Dried maca root is 59% carbohydrates, protein 10.2%, 8.5%Fibers and 2.2% lipids including linolenic acid, palmitic and oleic. It also contains sterols such as campesterol, stigmasterol and beta-sitosterol, and large amounts of minerals such as iron, calcium and copper. Two polyunsaturated fatty acids and macamides Maca Maca is used as a marker compound. Macamides maca extract lipids and increased sexual activity and improve ED. This plant is also used as a stimulant Peruvian ginseng (although maca cited is not the sameGinseng family), because, as ginseng, maca increases strength, energy, endurance, libido and sexual function.
Yohimbe is a procedure of large evergreen tree in western Africa known as Pausinystalia yohimbe or Corynanthe Yohimbe. The relevant section of Yohimbe is the bark. The component that lends itself to effects yohimbine Yohimbe is an alkaloid. Yohimbe bark is about 6% yohimbine. Shares are an aphrodisiac, Yohimbe, which treat the blood vessels in the genitals, the nerve impulsesTransmission of genital tissues, and increased reflex excitability in the sacral region of the spinal cord. The lessor Yohimbine readily penetrates the central nervous system (CNS) and acts primarily by alpha-2-adrenergic receptor blockade. He monoamine oxidase (MOA) inhibitors and calcium channel blockade and peripheral serotonin receptor blocking effects. Yohimbine effects on impotence are both increasing the flow of blood from the penis and higher mean central sympatheticExcitatory impulses to the genital tissues.
Muira Puama (Ptychopetalum scanner developed / olacoides Ptychopetalum) is a small tree that grows to 5 meters high and dates of the Brazilian and other regions of the Amazon forest. The genus is Ptychopetalum short – only two species of trees of small businesses to grow in tropical South America and five in tropical Africa. The two varieties of South America, olacoides P. (public holiday in Brazil, Guyana, Guyana and Suriname) and P. uncinatum(otherwise only in Brazil) plans are interchangeable herbal medicines in South America. Species olacoides is usually chosen because it is a higher content of lupeol (one of the active phytochemicals in the plant ha). A kind of disassociate myself completely from the structure ovata Liriosma Brazilian is also the common name of Muira puama (and is often used in trade as such), but is a completely different with a different phytochemical constitution.
Historicallyall components of Muira Puama has been used in medicine but the bark and roots are the parts most commonly used in the plant. The roots and bark are (in fatty acids and esters of fatty acids, the first is the Behenic acid), essential oils (including beta-and alpha-Caryophyllene Humulene), plant sterols, triterpenes (including lupeol), and a muirapuamina alkaloid called. The active components also free fatty acids, long chain, sesquiterpenes, monoterpenes, and newAlkaloids.
Revision belong to the main plant chemicals found in Muira Puama: Alpha-copaene, elemen-alpha, alpha Guaiene, alpha-Humulene, Muurolene, alpha-pinene, alpha-resin acid, alpha-terpinene, arachidic, the aromadendrene – Behenic acid, beta-Limonene, beta-Caryophyllene, beta-pinene, beta-resin acid, beta-sitosterol, beta-transfarnesene camphor, borneol, campesterol, camphene,, car-3-ene, caryophyllene, cerotic, chromium, coumarin, Cubebene, delta -Cadinene,Elixer dotriacontanoic acid, ergosterol, eugenol, essential oils, gamma-muurolene hentriacontanoic acid heptacosanoic, acid Lignoceric, limonene, linalool, lupeol, melissic acid, fatty acid Montan, muirapuamina, Myrcene, phlobaphen acid nonacosanoic, para-cymene pentacosanoic acid, stigmasterol, trichosanic acid and uncosanic acid.
Muira Puama speech is often used for the prevention of sexual disorders, and as an aphrodisiac. This raises the libido and improves the ability to maintainErection of the penis, and also acts as an adaptogen, anti-fatigue, anti-stress. Can be used alone or in combination with other herbs. It is also used (oral) in stimulating the nervous dyspepsia, menstrual disorders, rheumatism, paralysis caused by polio, caused as a general tonic and appetizer.
Damiana (Turnera diffusa / Damiana) is a shrub from Central America, Mexico, South America and the Caribbean. The medicinal part of this plant isits leaves are harvested during the flowering period. Damiana is found in Mexico, Central America and Caribbean, and parts of South America. Turnera diffuse aphrodisiaca T. are widely regarded as the same investment in the sector of trade in plants. A closely related species, T. ulmifolia is similar, but has used other conventional medicines. The Latin botanical name of the plant, Damiana reports on its use as an ancient aphrodisiac. With sucha long history of traditional customs from around the world, it is not surprising that the work appears in many books on herbal remedies screens around the world. Damiana is also widely purchased through health food stores and natural product diversity of forms – from blends of teas, capsules and tablets to liquid tinctures and extracts. Most doctors decide, Damiana herb used in combination with other herbs, so it can be satisfied with some formulas for the mix of vegetables from sexualPower to weight loss, depression, hormonal balance, and general tonic.
Damiana include components not less than 35 compounds including flavonoids, terpenes, saccharides, cyanogenic glycosides. Some of them belong triacontane, beta-sitosterol, Hexacosanol, 5-hydroxy-7 ,3,4-trimethoxyflavone, arbutin, tannins, resins, hydroquinone glycosides, luteolin 8-CE-acrylic acid and others.
DHEA (De-Hydro-Epi-Androsterone/dehydroepiandrosterone), is a natural hormone, steroid-pro –) Cholesterol by the adrenal glands, gonads, adipose tissue, brain and skin (by an autocrine mechanism. DHEA is the precursor of androstenedione, which happen to produce the result of the conversion of testosterone androgens and estrogens estrone and estradiol may too. DHEA is a potent sigma-1 agonists also. Spoken DHEA is used to retard or reverse aging, weight loss, metabolic syndrome and increased immune function and cognitive development. E 'also increasedPower, energy and muscle mass. Taking DHEA orally for 24 weeks improves ED, orgasm function, libido and general sexual satisfaction of men with erectile dysfunction.
Active parts of Tribulus terrestris, are the leaves, fruits and roots. Tribulus terrestris contains saponins such as diosgenin and protodioscin, flavonoids and alkaloids.Tribulus terrestris increases the levels of testosterone, luteinizing hormone (LH), DHEA, and di-hydro-testosterone. LH is the pituitary hormone that signals naturalThe production of testosterone. Thus, the libido and the production and sperm motility improved. Tribulus terrestris lowers blood pressure by inhibiting angiotensin converting enzyme (ACE) and the promotion of the release of NO. This also explains why the blood enters the corpora cavernosa, thereby enhancing the erection of the penis. Extracts from the fruits and leaves have a diuretic, which may explain the traditional use of Tribulus terrestris for kidney stones and other urinary tractProblems. Tribulus terrestris has anti-inflammatory effect, because it is a cyclooxygenase (COX) -2 inhibitor. Tribulus terrestris helps diabetic patients because it lowers levels of blood sugar. Some parts of Tribulus terrestris, also an anti-helmintic.
Deer Velvet Antler is one of the pillars of traditional Chinese medicine, ginseng probably only important. Velvet Antler is not the velvety "skin" the growth of the forest, but all the cartilage Antlercalcified in a syringe. In general, the forest near the base is cut off after about two thirds of the potential size and importance before calcification.
The wood is dried and used as a powder or tea for a series of promises of health. Velvet Antler is a stimulant, as an effective anti-inflammatory, anti-cancer, immune system, and the agent pro-growth.
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